| Characteristic | Details |
|---|---|
| Name | Diovan |
| Active Ingredient | Valsartan |
| Available Dosages | 40 mg, 80 mg, 160 mg, 320 mg |
| Form | Tablet |
| Indications | Hypertension, Heart Failure |
| Administration | Oral |
| Learn More About Diovan | |
Pharmacokinetics
Diovan 80 mg operates through its active ingredient, valsartan. It serves as an angiotensin II receptor blocker. Absorption occurs rapidly post-ingestion, although bioavailability sits at roughly 23%. Metabolism primarily occurs via the liver. The cytochrome P450 system minimally influences its pathway. Excretion involves biliary and renal routes. The drug’s half-life ranges from 6 to 9 hours.
Valsartan demonstrates significant protein binding, approximately 95%. Distribution throughout bodily tissues is efficient. Clearance involves fecal elimination of approximately 83% of an administered dose, while urine accounts for about 13%. The process maintains consistent levels across diverse demographics, regardless of age or sex.
Dosage Information
The typical starting dose for hypertension stands at 80 mg once daily. Patients may require adjustments up to 320 mg based on therapeutic response. Heart failure management starts with 40 mg twice daily. Dosage increments are gradual, observing patient tolerance. Clinicians base adjustments on individual efficacy and adverse reactions.
Renal function can influence dosing. Adjustments may be needed for patients with compromised kidney function. Liver impairment warrants similar considerations. In specific cases, lower starting doses might prevent excessive drug accumulation. The healthcare provider should monitor response and adjust accordingly.
FDA-Approved Indications
Diovan 160 mg received approval for hypertension management. It reduces stroke risk and myocardial infarction through effective blood pressure control. Additionally, it serves patients with heart failure. This medication aids those intolerant to angiotensin-converting enzyme (ACE) inhibitors.
Following a myocardial infarction, valsartan provides a viable therapeutic option. It aids in preventing cardiovascular events by curtailing blood pressure and promoting heart health. FDA recognition supports its use in enhancing patient quality of life.
Missed Dose
Patients missing a dose of Diovan should take it promptly. If the next dose approaches, skip the missed dose. Avoid doubling doses to prevent complications. Consistent administration maintains effective blood pressure control. Patients must adhere to their prescribed regimen.
Discuss any missed doses with healthcare professionals. Adjustments may be necessary to ensure optimal treatment efficacy. Monitoring is crucial to safeguard against hypertension risks.
Adverse Effects
Diovan 40 mg can lead to side effects. Common issues include dizziness, viral infections, and fatigue. Patients might experience abdominal pain or joint discomfort. Headaches are also reported. Regular monitoring by a healthcare professional is advisable.
Rare but serious effects encompass renal function deterioration and hyperkalemia. Severe hypotension may occur, particularly in volume-depleted patients. Anaphylaxis and angioedema, though uncommon, necessitate immediate medical intervention. Reporting side effects promptly aids in maintaining safety and efficacy.
For those considering Diovan for sale online, understanding these facets is crucial. Engage healthcare professionals to ensure the appropriate management of hypertension and heart failure. Accurate dosing and awareness of potential adverse effects enhance therapeutic outcomes.
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